Table 3 Univariate and multivariate analyses of prognostic factors

Variables	Number( n=180)	Univariate P	Multivariate analysis
HR (95% CI)	P
Age (year) (<60 vs ≥60)	131/49	0.061
Gender (male/female)	99/81	0.213
Tumor size (cm) (<5 vs ≥5)	109/71	0.015	1.676 (1.030–2.725)	0.038
Gross appearance (exophytic vs ulcerative vs infiltration)	55/20/105	0.926
Histological type (mucinous adenocarcinoma vs adenocarcinoma)	22/158	0.859
Tumor differentiation (III+IV vs I+II)	39/141	0.551
T (T1+T2 vs T3+T4)	15/165	0.104
Metastasis (absent vs present)	166/14	<0.001	4.812 (2.103–11.007)	<0.001
MOR expression (Score 0–1 vs Score 2–3)	85/95		1.832 (1.139–2.947)	0.013