Table 4.

Characteristics and differences of commercially available ⁹⁰Y-particles ¹⁵², ¹⁵⁶.

Feature	TheraSphere®	SIR-Spheres®
Isotope	90Y	90Y
Half-life (h)	64.2	64.2
Material	Glass	Resin
Diameter (μm)	20-30	20-60
Activity per particle (Bq)	2500	50
Spheres per 3 GBq	1.2 × 106	40-80 × 106
Activity in the vial (GBq)	3, 5, 7, 10, 15, or 20 %	3% ± 10%
Number of microspheres (vial, million)	1.2-8	40-80
Specific Gravity (g/mL)	3.2	1.6
Embolic effect	Negligible	Mild
Contrast injection	No	During infusion
FDA approved indication	Unresectable HCC	CRC liver metastases with intrahepatic floxuridine

FDA: Food and Drug Administration; CRC: Colorectal cancer; HCC: Hepatocellular carcinoma.