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. 2023 Apr 22;7(5):bvad056. doi: 10.1210/jendso/bvad056

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© The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Percent change from baseline over time in markers of insulin sensitivity data are estimated percentage means (SE) overtime, mITT (efficacy analysis set) ANOVA analysis (week 0), and MMRM analysis (week 40) using log transformation then convert back to original scale. *P < .05 and **P < .001 vs placebo at 40 weeks. Abbreviations: HOMA2-B, homeostatic model assessment for beta-cell function; IGFBP-2, insulin- like growth factor binding protein 2; mITT, modified intent-to-treat; MMRM, mixed-model repeated measures.