Table 3.
Mortality and kidney failure outcomes for new-onset kidney disease in each of the subset cohorts
| Deprived areas versus all other areas (case mix adjusted) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| eGFR <60 ml/min/1.73 m2 (n = 51 190) | eGFR <45 ml/min/1.73 m2 (n = 32 171) | eGFR <30 ml/min/1.73 m2 (n = 17 781) | AKI (n = 41 313) | ||||||||||
| Health outcomes (among all patients) | Events/cases (deprived), n/N | Events/cases (not deprived), n/N | Estimate (95% CI) | Events/cases (deprived), n/N | Events/cases (not deprived), n/N | Estimate (95% CI) | Events/cases (deprived), n/N | Events/cases (not deprived) | Estimate (95% CI) | Events/cases (deprived), n/N | Events/cases (not deprived), n/N | Estimate (95% CI) | |
| 1-year mortality OR (logistic regression model) | Age and sex adjusted | 499/3135 | 6395/48 055 | 1.33 (1.20–1.47) | 538/2080 | 7177/30 091 | 1.22 (1.10–1.35) | 488/1257 | 6089/16 524 | 1.21 (1.07–1.37) | 864/3210 | 10 862/38 103 | 1.18 (1.09–1.29) |
| Fully adjusted | 499/3135 | 6395/48 055 | 1.28 (1.15–1.43) | 538/2080 | 7177/30 091 | 1.19 (1.06–1.32) | 488/1257 | 6089/16 524 | 1.19 (1.05–1.35) | 864/3210 | 10 862/38 103 | 1.20 (1.09–1.31) | |
| Long-term mortality HR (Cox model) | Age and sex adjusted | 1167/3135 | 16 432/48 055 | 1.27 (1.20–1.35) | 1094/2080 | 15 712/30 091 | 1.18 (1.11–1.26) | 823/1257 | 11 044/16 524 | 1.15 (1.07–1.23) | 1644/3210 | 19 964/38 103 | 1.22 (1.16–1.28) |
| Fully adjusted | 1167/3135 | 16 432/48 055 | 1.21 (1.14–1.28) | 1094/2080 | 15 712/30 091 | 1.13 (1.06–1.20) | 823/1257 | 11 044/16 524 | 1.11 (1.04–1.19) | 1644/3210 | 19 964/38 103 | 1.18 (1.13–1.25) | |
| Long-term kidney failure HR (cause-specific Cox model) | Age and sex adjusted | 80/3135 | 716/48 055 | 1.50 (1.19–1.90) | 115/2080 | 1111/30 091 | 1.28 (1.06–1.56) | 170/1257 | 1854/16 524 | 1.07 (0.91–1.26) | 153/3210 | 1854/38 103 | 1.12 (0.95–1.32) |
| Fully adjusted | 80/3135 | 716/48 055 | 1.48 (1.17–1.87) | 115/2080 | 1111/30 091 | 1.29 (1.07–1.57) | 170/1257 | 1854/16 524 | 1.09 (0.93–1.28) | 153/3210 | 1854/38 103 | 1.12 (0.95–1.33) | |
Covariates adjusted in models were age at first presentation, sex and comorbidities (cancer, coronary heart disease, heart failure, stroke, atrial fibrillation, peripheral arterial disease, diabetes mellitus, hypertension, liver disease and chronic pulmonary disease).
Significant values is; bold type where statistically significant.