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. Author manuscript; available in PMC: 2023 May 4.
Published in final edited form as: Toxicol Appl Pharmacol. 2021 Feb 27;417:115470. doi: 10.1016/j.taap.2021.115470

Fig. 4.

Fig. 4.

Effects of anti-TNFα antibody administration on bleomycin-induced macrophage mobilization and activation in lung tissue. Panel A: Gating strategy used to identify myeloid subsets following F4/80 magnetic selection of collagenase digested tissue collected 7 d and 21 d post Bleo + CTL or Bleo + anti-TNFα exposure. Panel B: Quantification of total CD11b Interstitial Macrophages Panel C-E: Representative dot plot for CD11b and CD11c cells 7 d and 21 d post Bleo + CTL or Bleo + anti-TNFα exposure (Panel C); CD11b+CD11c+, interstitial macrophages (Panel D); and CD11b+CD11c− , immature macrophages (panel E) in the tissue 7 d and 21 d post Bleo + CTL or Bleo + anti-TNFα exposure. Data are represented as mean ± SD (n = 3). *Significantly different (p ≤ 0.05) from other groups.