TABLE 1.
Total IgE antibody titers in serum
| Study group | Total IgE (μg/ml) on daysa:
|
|||
|---|---|---|---|---|
| 0–3 | 7–9 | 10–11 | 14–22 | |
| V. cholerae O1-infected patients | ||||
| GM | 4.11 | 4.72 | 4.18 | 5.46 |
| Rangeb | 2.98–5.68 | 3.53–6.31 | 3.17–5.51 | 3.94–7.55 |
| nc | 20 | 20 | 20 | 20 |
| V. cholerae O139-infected patients | ||||
| GM | 2.64 | 2.17 | 4.04 | 2.30 |
| Range | 1.89–3.70 | 1.69–2.80 | 3.09–5.37 | 1.74–3.05 |
| n | 20 | 20 | 20 | 20 |
| ETEC-infected patients | ||||
| GM | 5.0 | 5.02 | ||
| Range | 3.76–6.68 | 3.99–6.32 | ||
| n | 15 | 13 | ||
| North American volunteers challenged with V. cholerae O1 | ||||
| GM | 0.13 | 0.13 | 0.15 | 0.13 |
| Range | 0.08–0.20 | 0.08–0.22 | 0.08–0.25 | 0.08–0.22 |
| n | 10 | 10 | 10 | 10 |
| Swedish cholera vaccinees | ||||
| GM | 0.05 | 0.045 | ||
| Range | 0.03–0.07 | 0.03–0.08 | ||
| n | 20 | 20 | ||
a
Days after onset of diarrhea or after oral challenge with live V. cholerae O1 or immunization with the bivalent B-O1/O139 WC cholera vaccine. Day 0 levels are preimmune levels.
b
Range is GM of IgE level ± 1 SEM.
c
n = number of study persons. The GM titer of total IgE in sera of healthy Bangladeshi controls (n = 26) was 4.45 μg/ml, and the range was 3.32 to 5.6 μg/ml.