Table 1.
Baseline characteristics of the two groups
| Variables | The LAAT/SEC group | The control group | P value |
|---|---|---|---|
| N = 98 | N = 471 | ||
| Age, years | 64.08 ± 10.65 | 61.68 ± 11.67 | 0.060 |
| Female, n (%) | 33 (33.67) | 166 (35.24) | 0.767 |
| Laboratory data | |||
| WBC count, 109/L | 7.00 ± 1.93 | 6.47 ± 1.35 | 0.001* |
| HB, g/L | 140.25 ± 17.60 | 139.47 ± 14.89 | 0.652 |
| Platelet count, 109/L | 208.19 ± 47.13 | 209.35 ± 51.11 | 0.837 |
| MPV, fL | 9.21 ± 1.06 | 9.04 ± 0.94 | 0.121 |
| Neutrophil count, 109/L | 4.68 ± 1.66 | 3.98 ± 0.99 | < 0.001* |
| Lymphocyte count, 109/L | 1.74 ± 0.63 | 1.91 ± 0.88 | 0.066 |
| Monocyte count, 109/L | 0.56 ± 0.72 | 0.43 ± 0.25 | 0.002* |
| HDL, mmol/L | 1.05 ± 0.27 | 1.12 ± 0.27 | 0.018* |
| Creatinine, µmol/L | 84.18 ± 27.25 | 80.47 ± 46.45 | 0.446 |
| Uric acid, µmol/L | 409.09 ± 123.39 | 393.87 ± 288.69 | 0.609 |
| eGFR, ml/ (min 1.73 m2) | 79.57 ± 22.72 | 87.26 ± 29.51 | 0.015* |
| Echocardiographic parameters | |||
| LAD, mm | 44.47 ± 5.86 | 39.30 ± 5.39 | < 0.001* |
| LVEDD, mm | 48.46 ± 6.22 | 47.57 ± 5.36 | 0.149 |
| EF, % | 59.45 ± 9.93 | 63.63 ± 8.37 | < 0.001* |
| Medical history | |||
| Hypertension, n (%) | 54 (55.10) | 233 (49.47) | 0.310 |
| Diabetes mellitus, n (%) | 25 (25.51) | 92 (19.53) | 0.183 |
| Coronary heart disease, n (%) | 23 (23.47) | 82 (17.41) | 0.159 |
| Heart failure, n (%) | 45 (45.92) | 68 (14.44) | < 0.001* |
| Previous stroke/TIA, n (%) | 16 (16.33) | 24 (5.10) | < 0.001* |
| Peripheral arterial disease, n (%) | 10 (10.20) | 12 (2.55) | 0.001* |
| Chronic kidney disease, n (%) | 10 (10.20) | 22 (4.67) | 0.031* |
| Hyperthyroidism, n (%) | 8 (8.16) | 31 (6.58) | 0.573 |
| Medication | |||
| Dabigatran, n (%) | 27 (27.55) | 183 (38.85) | 0.035* |
| Rivaroxaban, n (%) | 60 (61.22) | 242 (51.38) | 0.076 |
| Warfarin, n (%) | 12 (12.24) | 36 (7.64) | 0.136 |
| Antiplatelet, n (%) | 8 (8.16) | 11 (2.34) | 0.009* |
| NLR | 3.05 ± 1.67 | 2.31 ± 0.88 | < 0.001* |
| MHR | 0.54 ± 0.53 | 0.40 ± 0.21 | < 0.001* |
| CHADS2 Score | 1.96 ± 1.47 | 1.20 ± 1.33 | < 0.001* |
| CHA2DS2-VASc Score | 2.88 ± 1.74 | 2.06 ± 1.63 | < 0.001* |
Abbreviations: WBC: white blood cell; HB: hemoglobin; MPV: mean platelet volume; HDL: high-density lipoprotein; eGFR: estimated glomerular filtration rate; LAD: left atrial diameter; LVEDD: left ventricular end-diastolic diameter; EF: ejection fraction; TIA: transient ischemic attack; NLR: neutrophil-lymphocyte ratio; MHR: monocyte to high-density lipoprotein ratio; *: with statistical significance