Table 3.

Number of overlapping differentially expressed gene sets or pathways for muscle samples sequenced with standard reagents and CoolMPS reagents at MGI subjected to GSEA analysis across different group comparisons

Comparison
RP2-4 Visit 2 (n = 3) vs. Visit 1 (n = 3)	RT (n = 17) vs. C (n = 5)	RT-AS ≤ 2 (n = 15) vs. C (n = 5)	RT-AS ≥ 10 (n = 11) vs. C (n = 5)	RT-AS ≤ 2 (n = 15) vs. RT (n = 17)	RT-AS ≥ 10 (n = 11) vs. RT (n = 17)	RT-AS ≤ 2 (n = 15) vs. RT-AS ≥ 10 (n = 11)	Gene Set or Pathway
0	0	0	0	0	0	0	Hallmark
0	0	1	0	12	2	0	KEGG
0	0	0	0	74	0	1	Reactome
0	0	14	0	176	0	2	GO BP
0	0	6	0	120	0	8	GO MF

Gene sets or pathways with a false discovery rate (FDR) < 0.05 were reported as differentially expressed. GSEA: Gene Set Enrichment Analysis; UoB: University of Brighton; RP: Returning Participant; C: non-resistance trained control group; RT: Resistance Trained control group; RT-AS ≤ 2: Resistance Trained participant who self-declared AAS exposure ceased ≤ 2 weeks before sampling; RT-AS ≥ 10: Resistance Trained participant who self-declared AAS exposure ceased ≥ 10 weeks before sampling; GO BP: subset of GO biological processes; GO MF: subset of GO molecular functions