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. 2022 Oct 10;25(5):984–994. doi: 10.1093/neuonc/noac229

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Figure 4. — Kaplan–Meier curves for PFS and OS separated by MRI changes according to RANO criteria after two cycles of lomustine-based chemotherapy. Responders (ie, MRI changes consistent with Complete/Partial Response or Stable Disease according to RANO criteria) had a significantly longer PFS (8.0 vs. 2.9 months; P < .001) and OS (26.5 vs. 8.8 months; P = .002) than non-responders (ie, Progressive Disease according to RANO criteria).