Table 1.
Clinical characteristics of the participants according to TyG index tertiles.
| Total | TyG index |
p Value | |||
|---|---|---|---|---|---|
| Tertile 1 (7.32–8.33) | Tertile 2 (8.34–8.81) | Tertile 3 (8.82–10.32) | |||
| Number of participants, (n) | 151 | 50 | 50 | 51 | – |
| Sex (male/female), (n) | 84/67 | 30/20 | 25/25 | 29/22 | 0.589 |
| Age, (y) | 56.66 ± 12.43 | 56.80 ± 12.62 | 56.38 ± 12.82 | 56.78 ± 12.10 | 0.982 |
| BMI, (kg/m2) | 22.70 ± 3.75 | 22.13 ± 3.32 | 22.04 ± 3.02 | 23.91 ± 4.49 | 0.017 |
| Smoking, n (%) | 30 (19.87%) | 7 (14.00%) | 11 (22.00%) | 12 (23.53%) | 0.437 |
| Alcohol consumption, n (%) | 28 (18.54%) | 10 (20.00%) | 11 (22.00%) | 7 (13.73%) | 0.535 |
| Hypertension, n (%) | 120 (79.47%) | 41 (82.00%) | 43 (86.00%) | 36 (70.59%) | 0.137 |
| SBP, (mmHg) | 144.77 ± 23.15 | 149.76 ± 21.67 | 139.24 ± 22.49 | 145.31 ± 24.41 | 0.073 |
| DBP, (mmHg) | 80.70 ± 11.48 | 84.48 ± 10.63 | 77.54 ± 10.07 | 80.08 ± 12.69 | 0.009 |
| Fasting plasma glucose, (mmol/L) | 4.70 (4.20–5.10) | 4.55 (4.00–4.83) | 4.55 (4.20–5.10) | 4.90 (4.30–5.90) | 0.004 |
| Triglyceride, (mmol/L) | 1.39 (0.95–2.13) | 0.82 (0.62–1.03) | 1.39 (1.24–1.58) | 2.41 (2.12–3.08) | <0.001 |
| TyG index | 8.55 (8.17–9.03) | 8.04 (7.72–8.18) | 8.53 (8.42–8.70) | 9.14 (9.02–9.49) | <0.001 |
| Total cholesterol, (mmol/L) | 4.33 ± 1.04 | 4.08 ± 0.92 | 4.50 ± 1.11 | 4.40 ± 1.05 | 0.110 |
| HDL-C, (mmol/L) | 1.09 (0.91–1.32) | 1.26 (0.98–1.44) | 1.09 (0.87–1.31) | 1.00 (0.84–1.10) | <0.001 |
| LDL-C, (mmol/L) | 2.13 ± 0.74 | 1.89 ± 0.60 | 2.28 ± 0.77 | 2.20 ± 0.78 | 0.021 |
| Hemoglobin, (g/L) | 104.15 ± 18.31 | 103.64 ± 15.93 | 103.80 ± 19.19 | 104.98 ± 19.87 | 0.923 |
| Albumin, (g/L) | 41.90 (39.60–44.60) | 41.90 (39.10–44.93) | 41.75 (39.75–44.13) | 42.10 (39.60–44.60) | 0.852 |
| Alkaline phosphatase, (U/L) | 73.20 (57.00–94.00) | 66.50 (54.75–81.00) | 76.50 (59.50–103.00) | 78.00 (60.00–98.00) | 0.068 |
| 25(OH)D3, (ng/ml) | 29.31 ± 11.65 | 30.47 ± 11.48 | 28.81 ± 12.31 | 28.67 ± 11.29 | 0.693 |
| Calcium, (mmol/L) | 2.18 (2.08–2.31) | 2.17 (2.08–2.27) | 2.17 (2.03–2.30) | 2.26 (2.09–2.38) | 0.174 |
| Phosphorus, (mmol/L) | 1.98 ± 0.58 | 1.84 ± 0.51 | 1.91 ± 0.53 | 2.17 ± 0.65 | 0.012 |
| UA, (μmol/L) | 421.00 (372.00–484.00) | 407.50 (366.75–447.50) | 415.00 (372.25–490.50) | 443.00 (401.00–502.00) | 0.071 |
| CRP, (mg/L) | 0.81 (0.50–5.08) | 0.50 (0.50–1.28) | 1.03 (0.50–7.63) | 2.52 (0.50–7.06) | <0.001 |
| Ferritin, (ng/ml) | 97.69 (48.90–231.65) | 141.49 (46.84–272.49) | 85.49 (48.68–220.07) | 95.70 (47.45–146.38) | 0.399 |
| PTH, (pg/mL) | 221.40 (108.40–392.00) | 203.25 (79.03–333.23) | 168.65 (99.33–377.55) | 336.00 (166.50–445.80) | 0.013 |
| Phosphorus binder therapy, n (%) | 14 (9.27%) | 3 (6.00%) | 3 (6.00%) | 8 (15.69%) | 0.152 |
| Duration of dialysis, (month) | 49.00 (21.00–99.00) | 42.00 (22.00–77.25) | 41.00 (17.75–78.75) | 67.00 (35.00–121.00) | 0.032 |
| Kt/V | 1.26 ± 0.04 | 1.27 ± 0.04 | 1.26 ± 0.03 | 1.26 ± 0.03 | 0.087 |
| Presence of CAC, n (%) | 127 (84.11%) | 36 (72.00%) | 44 (88.00%) | 47 (92.16%) | 0.016 |
| CACS | 302.20 (29.60–976.32) | 66.53 (0–469.18) | 247.76 (37.35–827.61) | 666.58 (165.10–2523.46) | <0.001 |
BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; UA: uric acid; CRP: C-reactive protein; PTH: parathyroid hormone; Kt/v: fractional clearance index for urea; CAC: coronary artery calcification; CACS: coronary artery calcification score.