Table 5.
Alexithymia review results
| Authors | Publication year | Tool used to assess alexithymia | Genes | Polymorphisms studied | Genetic association | Sample population |
|---|---|---|---|---|---|---|
| Gong et al. | 2014 | TAS | 5-HTR1A | rs6295 | G | 504 Chinese Han students |
| Ham et al. | 2005 | TAS | SLC6A4, COMT | rs4680, 5-HTTLPR biallelic | COMT: GG | 109 students from Korea |
| Kano et al. | 2012 | TAS | SLC6A4 | 5-HTTLPR biallelic | L | 304 healthy Japanese participants |
| Koh et al. | 2016 | TAS | COMT | rs4680 | GG (both on total score and in subscores) | 244 patients with OCD from Korea |
| Koh et al. | 2015 | TAS | OXTR | rs237885, rs237887, rs2268490, rs4686301, rs2254298, rs13316193, rs53576, and rs2268498 | - | 355 patients with obsessive-compulsive disorder (234 men, 121 women) from Korea |
| Li et al. | 2020 | TAS | 5-HTR2A | rs6311 | rs6311 | 602 Han Chinese |
| Mandelli and Serretti | 2013 | SPSS | SLC6A4 | rs25531 | - | 64 Italians with alchohol and other substances abuse history |
| Roelofs et al. | 2015 | BVAQ | Rasopathies, Turner | Noonan Syndrome and Turner Syndrome (X0) | X0 | Females only sample, Dutch. 40 individuals with Turner Syndrome, 40 with Noonan Syndrome and 40 controls. |
| Sacchinelli et al. | 2018 | TAS | SLC6A4 | 5-HTTLPR biallelic | - | 115 healthy Italians |
| Schneider-Hassloff et al. | 2016 | CAS | OXTR | rs53576 | - | 195 Germans |
| Swart et al. | 2011 | BVAQ | COMT | rs4680 | AA (only in verbalizing subscale) | 493 undergraduate university students from Netherlands |
| Terock et al. | 2018 | TAS | SLC6A4 | 5-HTTLPR triallelic (rs25531G coded equivalent to S) | L | 5283 Germans |
| Terock et al. | 2021 | TAS | VDBP | rs4588, rs7041 | - | 5783 Germans |
| Terock et al. | 2021 | TAS | 5-HTR1A, 5-HTR2A | 5HTR1A: rs6295 5-HTR2A: rs6311 | - | 3708 Germans |
| van Rijn et al | 2006 | BVAQ | Klinefelter | XXY | XXY | 32 Klinefelter and 26 male controls (Dutch) |
| Voigt et al. | 2015 | TAS | BDNF, DRD2/ANKK1 | rs1800497, rs6265 | - | 143 healthy individuals |
| Wahlstrom et al. | 2012 | TAS | DRD2/ANKK1 | rs1800497 | - | 120 Undergraduate classified as ‘binge drinkers’ from the USA |
| Walter et al. | 2011 | TAS | BDNF, DRD2/ANKK1 | rs6265, rs1800497 | - (association present only in combination) | 664 Germans |
| Wingbermühle et al. | 2012 | TAS, BVAQ | Rasopathies | Noonan Syndrome and Turner Syndrome (X0) | Noonan Syndrome | 40 Dutch with Noonan Syndrome (various genes) and 40 controls |
| Zou et al. | 2019 | TAS | BDNF | rs6265 | AA (both cases and controls) | 223 Han Chinese people with panic disorder and 218 controls |