Table 2.
eConsults coded by question posed to specialist
| Reaction | Total (%) |
|---|---|
| Pre-existing diagnosis of allergy to non-COVID-19 vaccine | 205 (41.1) |
| Potential IgE-mediated allergic reactions | |
| Other vaccines | 62 (12.4) |
| Medications | 47 (9.4) |
| Polyethylene glycol | 14 (2.8) |
| Food | 14 (2.8) |
| Radiocontrast media | 14 (2.8) |
| Stinging insect | 1 (0.2) |
| Other | 9 (1.8) |
| Non-IGE-mediated allergic reaction | |
| Type IV (Delayed) non-polyethylene glycol allergen | 5 (1.0) |
| Type IV (Delayed) to polyethylene glycol | 0 (0.0) |
| Other | 4 (0.8) |
| Non-allergic reactions | |
| Other vaccines | 35 (7.0) |
| Pre-existing medical comorbidities | 74 (14.8) |
| Immune-related | |
| Autoimmune disease | 9 (1.8) |
| Secondary immunodeficiency | 9 (1.8) |
| Primary immunodeficiency | 3 (0.6) |
| Immunosuppressive therapy | 2 (0.4) |
| Pregnancy | 1 (0.2) |
| Non-immune-related | |
| Thromboembolic disease or hypercoagulability | 17 (3.4) |
| Cutaneous conditions | 6 (1.2) |
| Cancers | 0 (0.0) |
| Other | 27 (5.4) |
| Adverse Reaction to Dose 1 of COVID Vaccine | 180 (36.1) |
| Potential IgE-mediated allergic reactions | |
| Subjective or objective immediate angioedema, dyspnea, rashes, GI symptoms, or pre-syncope/syncope | 34 (6.8) |
| Non-IgE-mediated allergic reaction | |
| Delayed skin rashes | 54 (10.8) |
| Other | 10 (2.0) |
| Non-Allergic reaction | |
| Neurological (Numbness, Tingling) | 27 (5.4) |
| Delayed Flu-like Symptoms | 11 (2.2) |
| Myocarditis | 3 (0.6) |
| Other | 38 (7.6) |
| Questions Regarding Potential Vaccine Exemption | 15 (3.0) |
| Pediatric Age-Related Concerns | 1 (0.2) |
| General Anxiety about COVID-19 Vaccination | 7 (1.4) |
| Mixing of COVID-19 Vaccines | 0 (0.0) |
| Administration-Related Concerns | 9 (1.8) |
| Other | 8 (1.6) |
| TOTAL | 499 |
IgE = Immunoglobulin E, COVID-19 = coronavirus disease 2019 cause by the novel coronavirus SARS-CoV-2, GI = gastrointestinal