Fig. 2.

Decision guide for acute heavy menstrual bleeding (defined as any menstrual bleeding that interferes with daily activity [work, housework, leisure or sport, social activity] during most menstrual periods; bleeding is significant for any 1 of these scenarios: changing pads within 2 h, bleeding lasting ≥ 7 d, clot size > 1 cm with “flooding,” pictorial blood assessment chart score > 100).³⁴ F = factor; IV = intravenously; SC = subcutaneously; vWD = von Willebrand disease; vWF = von Willebrand factor.