13. NMA results for PFS (MSKCC favourable risk group).
Results of network meta‐analysis for outcome progression‐free survival (MSKCC favourable risk group). Treatments are ordered by P‐Score (descending). Only subnetworks with >1 designs. Upper triangle: direct estimate. Lower triangle: network estimate. Subnet 1 No. of studies: 7. No. of pairwise comparisons: 7. No. of treatments: 6. No. of designs: 5 Heterogeneity/Inconsistency: Q = 6.16, df = 2, P = 0.046; I² = 67.6%, Tau² = 0.3473 Treatment Effects + 95%‐CIs (Hazard ratios, random‐effects model): | |||||||
LEN+PEM | . | 0.36 [0.11, 1.23] | . | . | . | ||
0.80 [0.14, 4.54] | LEN+EVE | 0.45 [0.13, 1.53] | . | . | . | ||
0.36 [0.11, 1.23] | 0.45 [0.13, 1.53] | SUN | . | 0.59 [0.23, 1.55] | 0.50 [0.19, 1.33] | ||
0.28 [0.04, 2.10] | 0.35 [0.05, 2.61] | 0.79 [0.16, 3.81] | AXI | . | 0.64 [0.18, 2.23] | ||
0.21 [0.04, 1.02] | 0.27 [0.06, 1.26] | 0.59 [0.23, 1.55] | 0.75 [0.12, 4.78] | EVE | . | ||
0.18 [0.04, 0.87] | 0.23 [0.05, 1.08] | 0.50 [0.19, 1.33] | 0.64 [0.18, 2.23] | 0.85 [0.22, 3.32] | SOR | ||
Subnet 2 No. of studies: 2. No. of pairwise comparisons: 2. No. of treatments: 3. No. of designs: 2 Heterogeneity/Inconsistency: Q = 0.0, df=0, P = n.a.; I² = n.a., Tau² = n.a. Treatment Effects + 95%‐CIs (Hazard ratios, random‐effects model): | |||||||
IFN+BEV | 0.83 [0.59, 1.18] | 0.60 [0.42, 0.85] | |||||
0.83 [0.59, 1.18] | TEM+BEV | . | |||||
0.60 [0.42, 0.85] | 0.72 [0.44, 1.18] | IFN+PLA |