Fig. 3. ClO4− at low concentrations is transported electrogenically by NIS.
(a) Current/voltage relationships recorded by TEVC in oocytes expressing NIS upon addition of I− (160 μM), in the presence or absence of ClO4− (0.3 μM) in the bath solution. (b) Effect of ClO4− (0.3 μM) on current/voltage relationships recorded by TEVC in oocytes expressing NIS or SMIT. (c) Current/voltage relationships recorded by TEVC in oocytes expressing NIS with 0.1-500 μM ClO4− in the bath solution. Error bars indicate SEM (n = 8-10).