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. 2023 May 4;18(5):e0285012. doi: 10.1371/journal.pone.0285012

Fig 5. Antagonistic effect of Ocimum tenuiflorum extract with CRF1 receptor.

Fig 5

Ocimum tenuiflorum extract at different non-cytotoxic concentrations was tested using human recombinant (CHO) cells containing CRF1 receptors. The antagonistic effect was assessed by analyzing the levels of cAMP using a HTRF detection method. Reduction in the levels of cAMP is presented as the percentage of CRF1 activity inhibited. The higher the percentage of CRF1 activity inhibited, the better the antagonistic effect.