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. 2023 Apr 24;19(4):e1011022. doi: 10.1371/journal.pcbi.1011022

Fig 4. MultiCens on human multilayer networks: Ground-truth validation.

Fig 4

(A) Recall (# of ground truth genes recovered; y-axis) in the top k ranked genes (x-axis) are plotted using MultiCens query-set centrality based ranking vis-à-vis a random ranking (random curve). Only primary hormones shown here; see Fig B in S1 Text for comparison with other methods, and Fig C in S1 Text for plots for the other tested hormones. (B) For hormones with 10 or more genes in either producing or responding set, the smaller set is used as the query-set, and the plot reports AUC score for predicting the bigger set (marked in bold-face font in x-axis). For the four primary hormones having at least 10 genes on both producing and responding sets, plot reports AUC for predicting both sets. See also Table A in S1 Text.