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. 2023 Apr 10;8(5):875–888. doi: 10.1038/s41564-023-01346-6

Extended Data Fig. 3. Enriched motifs of Sensitized and Resolved-specific DARs, related to Fig. 3 and Fig. 5.

Extended Data Fig. 3

(A-B) HOMER motif analysis using USC ATAC-seq data (Fig. 4a) generated lists of enriched TF binding motifs in Sensitized-accessible DARs (A) and Resolved-accessible DARs (B) with their p-values. HOMER scanned the sequences of DARs for known motifs and calculate enrichment score p-value using binomial test. HOMER also discovered de novo motifs with their best matches to a known motif in DARs. Each Top 10 known and de novo motifs enriched in Sensitized (A) and Resolved USCs (B) are shown with their sequence logo and p-value.