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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Lung Cancer. 2023 Mar 22;179:107180. doi: 10.1016/j.lungcan.2023.107180

Figure 1.

Figure 1.

Differentially expressed genes and common canonical pathways associated with transformation of HBEC lines by the Kentucky reference cigarette (KRC) and e-liquids. A. Number of genes with increased or decreased expression across HBEC2, HBEC4, and HBEC26 transformed by Jamestown (JT), Blue Pucker (BP), Unflavored (UF) or the KRC. B. Venn diagrams showing common and distinct genes differentially expressed between transformed clones from HBEC4/HBEC26 exposed to KRC, HBEC2/HBEC26 exposed to JT, and HBEC26 exposed to JT, BP, or UF. C. Significantly altered pathways comprised of common genes from transformed clones from HBEC4/HBEC26 exposed to KRC, HBEC2/HBEC26 exposed to JT, and HBEC26 exposed to JT, BP, or UF.