Table 4.
Top Five Categories of Molecular and Cellular Functions Altered in Transformed Cigarette and E-cigarette Clones
| Product(s) | Molecular & Cellular Function1 | −log10 p-value | #Genes |
|---|---|---|---|
| Jamestown (HBEC2/HBEC26) | Cell Movement | 15.0 | 136 |
| Cell Death & Survival | 11.1 | 147 | |
| Cellular Development | 8.8 | 132 | |
| Cell Growth & Proliferation | 7.3 | 134 | |
| Lipid Metabolism | 5.9 | 54 | |
| Jamestown Blue Pucker Unflavored (HBEC26) | Cell Movement | 44.5 | 321 |
| Cell Death & Survival | 21.0 | 325 | |
| Cell Assembly & Organization | 16.8 | 242 | |
| Cell Function & Maintenance | 16.8 | 277 | |
| Cell-to-Cell Signaling | 16.5 | 248 | |
| Kentucky Reference Cigarette (HBEC4/HBEC26) | Cell Movement | 66.0 | 656 |
| Cell Death & Survival | 47.5 | 748 | |
| Cell Assembly & Organization | 42.0 | 535 | |
| Cell Function & Maintenance | 42.0 | 473 | |
| Cell Development | 33.5 | 810 |
1
Derived from common differentially expressed genes across product(s).