Table 1.
Baseline characteristics and procedural results of real-world and RCT patients
| Characteristics | GSR-anterior N = 4666 |
GSR-VB N = 569 |
VISTA N = 717 |
|---|---|---|---|
| Age, median (IQR) (years) | 76 (66–83) | 75 (65–82) | 68 (57–76) |
| Female, no. (%) | 2414 (51.7) | 244 (43.0) | 325 (45.3) |
| Medical history, no. (%) | |||
| Hypertension | 3585 (77.6) | 450 (80.5) | 380 (53.2) |
| Diabetes mellitus | 1032 (22.3) | 116 (21.1) | 95 (13.3) |
| Dyslipidemia | 1876 (40.6) | 215 (39.1) | 228 (32.8) |
| Atrial fibrillation | 1987 (43.1) | 188 (33.8) | – |
| Current smoking | 653 (17.1) | 74 (13.0) | 194 (28.4) |
| Drug use, no. (%) | |||
| Oral anticoagulation | 982 (21.5) | 88 (16.2) | – |
| Antiplatelet agents | 1429 (31.3) | 202 (37.2) | – |
| Pre-stroke mRS score, median (IQR) | 0 (0–1) | 0 (0–1) | 0 (0–0) |
| Baseline NIHSS score, median (IQR) | 15 (10–18) | 16 (7–26) | 17 (14–20) |
| Left side, no. (%) | 2414 (51.9) | NA | – |
| Affected vessel, no. (%) | |||
| M1 | 2818 (60.4) | NA | – |
| M2 | 1085 (23.3) | NA | – |
| ICA | 564 (12.1) | NA | – |
| ICA-T | 842 (18.0) | NA | – |
| Basilar artery | NA | 532 (93.5) | – |
| Vertebral artery only | NA | 37 (6.5) | – |
| General anesthesia, no. (%) | 2946 (65.2) | 493 (89.2) | – |
| Ship to interventional center, no. (%) | 1970 (42.2) | 235 (41.3) | – |
| Symptom onset known, no. (%) | 2830 (60.7) | 345 (60.6) | – |
| Out of hour admission, no. (%) | 2772 (59.4) | 324 (56.9) | – |
| High volume center, no. (%) | 2873 (61.6) | 367 (64.5) | – |
| ASPECTS, no. (%) | |||
| High (9–10) | 2205 (52.6) | NA | 349 (48.7) |
| Middle (6–8) | 1593 (38.0) | NA | 301 (42.0) |
| Low (0–5) | 377 (9.0) | NA | 67 (9.3) |
| Intravenous alteplase treatment, no. (%) | 2414 (52.0) | 258 (45.6) | 642 (89.5) |
| Symptom onset to arterial puncture, median (IQR) (min) | 220 (153–334) | 252 (164–399) | 181 (142–237) |
| mTICI, no. (%) | |||
| 3 | 2282 (49.6) | 344 (62.3) | – |
| 2b | 1609 (34.9) | 133 (24.1) | – |
| 0–2a | 714 (15.5) | 75 (13.6) | – |
mRS modified Rankin Scale, IQR interquartile range, NIHSS National Institutes of Health Stroke Scale, M1/2 first/second segment of the middle cerebral artery, ICA internal carotid artery, ICA-T internal carotid artery T, ASPECTS Alberta Stroke Program Early CT Score, min minutes, mTICI modified Thrombolysis in Cerebral Infarction, VB vertebrobasilar