Figure 2 .

circ-BPTF is upregulated in the lung and smooth muscle of COPD patients

Lung tissues were collected from COPD or control patients. Total RNA was isolated, and circRNA microarray hybridization was performed based on Arraystar’s standard protocols. (A) Heatmap and volcano map analysis of circular RNAs in lung tissues from COPD patients and controls. (B-E) qPCR analysis of the expressions of four circRNAs in lung tissues from COPD patients and controls (n=6). (F) Fluorescence in situ hybridization of circ-BPTF in lung tissues from COPD patients. * P<0.05.