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. 2023 Apr 21;14:1144945. doi: 10.3389/fgene.2023.1144945

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Copyright © 2023 Tang, An, Gu, Yi, Hu, Wu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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H&E and DEGs between tumor and NSG tissues. (A) The histopathological features of the ACCs and NSG used in this study (H&E, 40x). (B) PCA plots showing clustering of 28 samples (13 NSG and 15 ACCs). (C) Sample distances showing clustering of 28 samples (13 NSG and 15 ACCs) (tumor_classic: ACC with a pathological type of cribriform-tubular and cribriform; tumor_rare: ACC with a pathological type of sold and high-grade transformation). (D) Volcano plot of the DEGs. The red (top) and blue (down) sites reflect the differentially expressed RNAs with log fold-change>│5│and PDR Q < 0.05.