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. 2023 Apr 21;14:1144945. doi: 10.3389/fgene.2023.1144945

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Copyright © 2023 Tang, An, Gu, Yi, Hu, Wu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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mRNAs isoform analysis. (A) A total of 1690 isoforms were identified for all significant genes. (B) A total of 1336 isoforms were identified with potential functional consequences. (C–E) Genome-wide analysis of isoform switches and their predicted consequences. (F–H) Genome-wide analysis of alternative splicing and changes. (I) Analysis of the biological mechanisms behind isoform switching. (J–N) Top genes associated with isoform switching.