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. 2023 Apr 21;14:1184250. doi: 10.3389/fphar.2023.1184250

TABLE 1.

Correlation between CNN1 and clinicopathologic characteristics.

Clinicopathologic characteristics n CNN1 expression p-value
Low High
Sex Male 34 19 15 0.423
Female 16 7 9
Age (years) <60 9 5 4 0.814
≥60 41 21 20
Histological type Adenocarcinoma 34 17 17 0.680
Mucoid adenocarcinoma 16 9 7
Depth of tumor invasion T1 and T2 12 10 2 0.013
T3 and T4 38 16 22
Degree of differentiation High and moderately differentiated 20 12 8 0.355
Poorly differentiated 30 14 16
Tumor size <5 cm 27 16 11 0.266
≥5 cm 23 10 13
TNM staging Ⅰ and Ⅱ stage 30 28 8 <0.001
Ⅲ and Ⅳ stage 20 4 16
Lymph node metastasis Without 32 22 10 0.002
With 18 4 14
CEA <5 ng/ml 35 20 15 0.266
≥5 ng/ml 15 6 9
CA 19-9 <37 U/ml 44 29 19 0.065
≥37 U/ml 6 1 5