Fig. 3.

Abdala vaccine efficacy to prevent symptomatic COVID-19. Secondary end-points and Subgroups analyses. Analysis of Abdala's efficacy in the prevention of symptomatic COVID-19 by clinical forms of the disease, death and various subgroups in the per-protocol population, was based on adjudicated assessments starting 14 days after the third injection. Vaccine efficacy, defined as 1 minus the hazard ratio (Abdala vs. placebo), and 95% confidence intervals were estimated with the use of a stratified Cox proportional-hazards model. The dashed vertical line represents a vaccine efficacy of 30%, based on the null hypothesis that the primary efficacy of Abdala vaccine is 30% or less.