Table 1.
Demographic and baseline characteristics of the participants in the ABDALA-3 study at enrolment.
| Variable | Placebo | Abdala vaccine | Total |
|---|---|---|---|
| N (%) | 24,144 (50.0) | 24,146 (50.0) | 48,290 (100) |
| Sex – no. (%) | |||
| Female | 12,689 (52.6) | 12,597 (52.2) | 25,286 (52.4) |
| Male | 11,455 (47.4) | 11,549 (47.8) | 23,004 (47.6) |
| Age (years) | |||
| Means ± SD | 48.9 ± 16.2 | 48.9 ± 16.1 | 48.9 ± 16.2 |
| Median (IQR) | 50 (15) | 50 (15) | 50 (15) |
| Ethnicity– no. (%) | |||
| White | 6248 (25.9) | 6357 (26.3) | 12,605 (26.1) |
| Black | 5233 (21.7) | 5266 (21.8) | 10,499 (21.7) |
| Mestizo | 12,633 (52.4) | 12,523 (51.9) | 25,186 (52.2) |
| BMI (kg/m2) | |||
| Means ± SD | 26.5 ± 4.4 | 26.5 ± 4.3 | 26.5 ± 4.3 |
| Median (IQR) | 26.4 (6.2) | 26.4 (6.2) | 26.4 (6.2) |
| Subjects with some comorbidity – no. (%) | 17,928 (74.3) | 17,931 (74.3) | 35,859 (74.3) |
| Main comorbidities/risk factors – no. (%) | |||
| Overweight/type I obesity | 11,806 (48.9) | 11,756 (48.7) | 23,562 (48.8) |
| High blood pressure | 8223 (34.1) | 8261 (34.2) | 16,484 (34.1) |
| Smoking | 6339 (26.3) | 6197 (25.7) | 12,536 (26.0) |
| Diabetes mellitus | 1959 (8.1) | 1945 (8.1) | 3904 (8.1) |
| Bronchial asthma | 1881 (7.8) | 1928 (8.0) | 3809 (7.9) |
| Heart disease | 897 (3.7) | 897 (3.7) | 1794 (3.7) |
| Other CNS and peripheral disorders | 878 (3.6) | 899 (3.7) | 1777 (3.7) |
| Allergy | 852 (3.5) | 853 (3.5) | 1705 (3.5) |
| Gastrointestinal disorders | 789 (3.3) | 799 (3.3) | 1588 (3.3) |
| COPD | 259 (1.1) | 243 (1.0) | 502 (1.0) |
| Cancer | 250 (1.0) | 227 (0.9) | 477 (1.0) |
| Ischemic/hemorrhagic cerebral infarction | 151 (0.6) | 163 (0.7) | 314 (0.7) |
| Genitourinary disorders | 149 (0.6) | 132 (0.5) | 281 (0.6) |
| Disorders of red blood cells and platelets | 85 (0.4) | 82 (0.3) | 167 (0.3) |
| Deep and superficial vein thrombosis | 28 (0.1) | 36 (0.1) | 64 (0.1) |
| Subjects with total antibodies against SARS-CoV-2 at baseline | 3986 (16.5) | 3951 (16.4) | 7937 (16.4) |
BMI: Body-mass index (the weight in kilograms divided by the square of the height in meters. The calculation was based on the weight and height measured at the time of screening); CNS: Central Nervous System; COPD: Chronic Obstructive Pulmonary Disease; IQR: Interquartile range; SD: standard deviation.