Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Three significant assumptions of depression on metabolites via reverse MR. The three paths represent these three different assumptions. Relevance assumption: SNPs are associated with depression (the exposure). Independence assumption: SNPs are completely independent of any potential confounding factors that influence depression and metabolites. Exclusivity assumption: SNPs affect metabolites only through depression (exposure) and not via any alternative causal pathways.
