Table 1.
Top 3 toxin gene families expressed in the venom gland of C. rhodostoma.
| Toxin abundance (%) | Swiss-Prot ID | Length (amino acid) | Annotated Description | Species | Identity (%) | E-value |
|---|---|---|---|---|---|---|
| snake venom metalloproteinase (SVMP) (61.29% of total toxin FPKM) | ||||||
| 33.16 | P0CB14 | 417 | Snake venom metalloproteinase kistomin | Calloselasma rhodostoma | 100.00 | 6.40E-141 |
| 27.31 | P30403 | 478 | Zinc metalloproteinase/disintegrin | Calloselasma rhodostoma | 100.00 | 1.30E-108 |
| 0.42 | Q8AWI5 | 610 | Zinc metalloproteinase-disintegrin-like halysase | Gloydius halys | 82.47 | 3.10E-251 |
| 0.18 | Q90ZI3 | 612 | Zinc metalloproteinase-disintegrin-like HV1 | Protobothrops flavoviridis | 90.72 | 8.60E-45 |
| 0.14 | Q7SZD9 | 478 | Zinc metalloproteinase/disintegrin ussurin | Gloydius ussuriensis | 76.86 | 1.90E-159 |
| 0.04 | P0DM87 | 484 | Zinc metalloproteinase-disintegrin stejnitin | Trimeresurus stejnegeri | 76.49 | 2.10E-113 |
| 0.03 | Q1PS45 | 608 | Zinc metalloproteinase-disintegrin-like agkihagin | Deinagkistrodon acutus | 89.32 | 1.10E-117 |
| <0.01 | Q2EI26 | 413 | Snake venom metalloproteinase AaPA | Deinagkistrodon acutus | 77.50 | 1.70E-09 |
| <0.01 | F8S108 | 610 | Zinc metalloproteinase-disintegrin-like 4a | Crotalus adamanteus | 96.00 | 1.40E-07 |
| <0.01 | C5H5D4 | 414 | Zinc metalloproteinase-disintegrin-like batroxstatin-3 (Fragment) | Bothrops atrox | 80.95 | 2.80E-25 |
| <0.01 | C5H5D5 | 421 | Zinc metalloproteinase-disintegrin-like lachestatin-1 | Lachesis muta rhombeata | 88.89 | 5.40E-07 |
| <0.01 | J3S829 | 612 | Zinc metalloproteinase-disintegrin-like 2a | Crotalus adamanteus | 79.26 | 1.30E-68 |
| <0.01 | Q6T271 | 325 | Zinc metalloproteinase/disintegrin (Fragment) | Bitis gabonica | 85.19 | 1.50E-06 |
| <0.01 | Q2LD49 | 621 | Zinc metalloproteinase-disintegrin-like TSV-DM | Trimeresurus stejnegeri | 72.50 | 5.60E-09 |
| <0.01 | Q8AWX7 | 488 | Zinc metalloproteinase-disintegrin agkistin | Gloydius halys | 90.32 | 2.10E-11 |
| <0.01 | Q9W6M5 | 610 | Zinc metalloproteinase-disintegrin-like acurhagin | Deinagkistrodon acutus | 78.13 | 1.20E-06 |
| <0.01 | A8QL59 | 621 | Zinc metalloproteinase-disintegrin-like NaMP | Naja atra | 70.18 | 2.90E-18 |
| snake venom C-type lectin/lectin-like protein (Snaclec) (12.38% of total toxin FPKM) | ||||||
| 5.50 | P81398 | 129 | Snaclec rhodocetin subunit beta | Calloselasma rhodostoma | 100.00 | 1.60E-72 |
| 3.36 | Q9I841 | 136 | Snaclec rhodocytin subunit alpha | Calloselasma rhodostoma | 100.00 | 1.70E-16 |
| 1.07 | P81397 | 133 | Snaclec rhodocetin subunit alpha | Calloselasma rhodostoma | 98.31 | 4.70E-65 |
| 1.07 | D2YW39 | 135 | Snaclec rhodocetin subunit gamma | Calloselasma rhodostoma | 97.04 | 5.20E-78 |
| 0.39 | D2YW40 | 124 | Snaclec rhodocetin subunit delta | Calloselasma rhodostoma | 98.36 | 6.40E-72 |
| 0.35 | Q8AYA5 | 158 | Snaclec agglucetin subunit alpha-2 | Deinagkistrodon acutus | 73.38 | 1.20E-57 |
| 0.21 | P0DM39 | 148 | Snaclec alboaggregin-D subunit beta | Trimeresurus albolabris | 60.61 | 4.40E-46 |
| 0.21 | Q9PSN0 | 135 | C-type lectin PAL | Bitis arietans | 83.46 | 4.40E-70 |
| 0.17 | A7X3Z7 | 163 | C-type lectin lectoxin-Lio2 | Erythrolamprus poecilogyrus | 45.07 | 5.30E-34 |
| 0.05 | Q9I840 | 146 | Snaclec rhodocytin subunit beta | Calloselasma rhodostoma | 100.00 | 4.30E-75 |
| 0.01 | Q6TPH0 | 158 | Snaclec mucrocetin subunit alpha | Protobothrops mucrosquamatus | 62.04 | 9.30E-36 |
| <0.01 | A7X3Z0 | 158 | C-type lectin lectoxin-Thr1 | Thrasops jacksonii | 39.66 | 4.70E-30 |
| <0.01 | D2YVJ8 | 158 | C-type lectin mannose-binding isoform | Tropidechis carinatus | 65.71 | 3.80E-08 |
| <0.01 | Q6QX33 | 158 | C-type lectin BiL | Bothrops insularis | 60.98 | 9.60E-07 |
| <0.01 | J3SBP0 | 157 | C-type lectin 9a | Crotalus adamanteus | 75.00 | 5.70E-14 |
| <0.01 | Q9PRY7 | 135 | C-type lectin BjL | Bothrops jararaca | 100.00 | 1.00E-09 |
| <0.01 | Q696W1 | 158 | Snaclec coagulation factor X-activating enzyme light chain 2 | Macrovipera lebetina | 67.65 | 5.00E-07 |
| <0.01 | C6JUN9 | 158 | C-type lectin | Micrurus corallinus | 42.95 | 3.00E-30 |
| <0.01 | B4XSY9 | 156 | Snaclec A14 | Macrovipera lebetina | 61.22 | 5.90E-11 |
| <0.01 | P81112 | 134 | Snaclec alboaggregin-A subunit alpha | Trimeresurus albolabris | 79.31 | 8.10E-07 |
| snake venom serine protease (SVSP) (11.57% of total toxin FPKM) | ||||||
| 6.84 | O13059 | 258 | Snake venom serine protease 1 | Trimeresurus gramineus | 92.31 | 2.30E-19 |
| 3.93 | P47797 | 258 | Thrombin-like enzyme ancrod-2 | Calloselasma rhodostoma | 100.00 | 1.10E-19 |
| 0.54 | P26324 | 234 | Thrombin-like enzyme ancrod | Calloselasma rhodostoma | 100.00 | 1.40E-57 |
| 0.09 | P05620 | 260 | Thrombin-like enzyme flavoxobin | Protobothrops flavoviridis | 85.37 | 1.70E-12 |
| 0.05 | Q8UVX1 | 260 | Snake venom serine protease gussurobin | Gloydius ussuriensis | 70.18 | 9.90E-43 |
| 0.03 | Q9I8X2 | 260 | Thrombin-like enzyme acutobin | Deinagkistrodon acutus | 52.10 | 2.20E-31 |
| 0.02 | Q8AY78 | 258 | Snake venom serine protease 5 | Trimeresurus stejnegeri | 79.59 | 4.90E-18 |
| 0.02 | O73800 | 260 | Snake venom serine protease salmobin | Gloydius halys | 64.86 | 1.80E-53 |
| 0.02 | Q2QA04 | 262 | Snake venom serine protease | Crotalus durissus durissus | 69.54 | 4.30E-53 |
| 0.01 | Q8AY81 | 260 | Thrombin-like enzyme stejnobin | Trimeresurus stejnegeri | 72.34 | 1.40E-12 |
| 0.01 | Q71QI3 | 257 | Snake venom serine protease CL5 | Trimeresurus stejnegeri | 77.27 | 2.40E-23 |
| 0.01 | E0Y420 | 258 | Serine protease VLSP-3 | Macrovipera lebetina | 88.14 | 2.70E-25 |
| <0.01 | Q802F0 | 258 | Snake venom serine protease PTLE1 | Gloydius halys | 86.21 | 1.90E-06 |
| <0.01 | A7LAC6 | 260 | Thrombin-like enzyme 1 | Trimeresurus albolabris | 62.50 | 5.00E-10 |