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. 2023 Apr 3;108(5):927–935. doi: 10.4269/ajtmh.22-0242

Table 1.

Susceptibility profile of Gram-negative rods recovered from urine samples

Tested antibiotics GNR Enterobacterales Group I EB Group II EB Group III EB NF-GNR
Nb Result Nb Result Nb Result Nb Result Nb Result Nb Result
ESBL-PE 2,092 106 (5.1%) 2,092 106 (5.1%) 1,572 75 (4.8%) 374 30 (8%) 146 1 (0.7%) 29 0 (0%)
Penicillins
 Ampicillin 2,100 608 (29%) 2,092 608 (29.1%) 1,572 608 (38.7%) 374 0 (0%) 146 0 (0%)
 Amoxicillin/clavulanic acid 2,099 1,566 (74.6%) 2,092 1,565 (74.8%) 1,572 1,240 (78.9%) 374 325 (86.9%) 146 0 (0%)
 Piperacillin 2,124 732 (34.5%) 2,092 706 (33.7%) 1,572 610 (38.8%) 374 0 (0%) 146 96 (65.8%) 29 26 (89.7%)
 Ticarcillin 2,125 752 (35.4%) 2,092 725 (34.7%) 1,572 629 (40%) 374 0 (0%) 146 96 (65.8%) 29 27 (93.1%)
 Piperacillin/tazobactam 2,124 2,012 (94.7%) 2,091 1,982 (94.8%) 1,571 1,502 (95.6%) 374 344 (92%) 146 136 (93.2%) 29 28 (96.6%)
 Temocillin 1,318 1,286 (97.6%) 1,317 1,286 (97.6%) 1,044 1,030 (98.7%) 193 186 (96.4%) 80 70 (87.5%)
 Mécillinam 1,055 970 (91.9%) 1,055 970 (91.9%) 1,004 933 (92.9%) 44 34 (77.3%) 7 3 (42.9%)
 Aztreonam 687 622 (90.5%) 669 611 (91.3%) 625 585 (93.6%) 37 21 (56.8%) 7 5 (71.4%) 16 11 (68.8%)
Cephalosporins
 Cefotaxime 2,096 1,971 (94%) 2,092 1,968 (94.1%) 1,572 1,495 (95.1%) 374 344 (92%) 146 129 (88.4%)
 Ceftazidime 2,126 2,011 (94.6%) 2,092 1,982 (94.7%) 1,572 1,507 (95.9%) 374 344 (92%) 146 131 (89.7%) 29 26 (89.7%)
 Cefepime 2,126 2,017 (94.9%) 2,092 1,984 (94.8%) 1,572 1,507 (95.9%) 374 346 (92.5%) 146 131 (89.7%) 29 29 (100%)
Carbapenems
 Imipenem 2,124 2,118 (99.7%) 2,091 2,086 (99.8%) 1,572 1,571 (99.9%) 374 374 (100%) 145 141 (97.2%) 29 29 (100%)
 Meropenem 121 120 (99.2%) 90 90 (100%) 48 48 (100%) 35 35 (100%) 7 7 (100%) 29 29 (100%)
 Ertapenem 2,080 2,076 (99.8%) 2,078 2,074 (99.8%) 1,567 1,567 (100%) 368 367 (99.7%) 143 140 (97.9%)
Aminoglycosides
 Amikacin 2,120 2,084 (98.3%) 2,089 2,054 (98.3%) 1,570 1,546 (98.5%) 373 364 (97.6%) 146 144 (98.6%) 29 28 (96.6%)
 Tobramycin 1,185 1,080 (91.1%) 1,154 1,049 (90.9%) 879 805 (91.6%) 203 183 (90.1%) 72 61 (84.7%) 29 29 (100%)
 Gentamycin 2,111 1,960 (92.8%) 2,080 1,929 (92.7%) 1,564 1,453 (92.9%) 373 351 (94.1%) 143 125 (87.4%) 29 29 (100%)
Fluoroquinolones
 Ofloxacin 2,097 1,710 (81.5%) 2,092 1,707 (81.6%) 1,572 1,256 (79.9%) 374 328 (87.7%) 146 123 (84.2%)
 Ciprofloxacin 1,977 1,797 (90.9%) 1,943 1,766 (90.9%) 1,449 1,311 (90.5%) 362 331 (91.4%) 132 124 (93.9%) 29 28 (96.6%)
Others
 TMP/SMX 2,097 1,402 (66.9%) 2,082 1,387 (66.6%) 1,567 955 (60.9%) 372 317 (85.2%) 143 115 (80.4%) 13 13 (100%)
 Nitrofurantoin 2,084 1,786 (85.7%) 2,083 1,785 (85.7%) 1,565 1,475 (94.2%) 373 238 (63.8%) 145 72 (49.7%)
 Fosfomycin 765 750 (98%) 764 749 (98%) 714 708 (99.2%) 43 35 (81.4%) 7 6 (85.7%)

EB = Enterobacteriaceae; ESBL = extended-spectrum β-lactamases; GNR = Gram-negative rods; Nb = number of tested isolates; NF-GNR = nonfermentative GNR; PE = producing enterobacterales; TMP/SMX = trimethoprim/sulfamethoxazole.