Table 1.

Main characteristics of the included observational studies in the scoping review

Study (country)	Study type	Aim	Outcome	Population	Comparative groups	Key findings	Limitations
Lorenzo et al., 2022 (Spain)	Longitudinal	To evaluate the frequency of strongyloidiasis in immigrants with COVID-19 and the clinical characteristics of these patients	Investigational	Patients > 18 years from strongyloidiasis endemic areas with COVID-19 (N = 86)	N/A	The use of dexamethasone in patients with COVID-19 did not affect the clinical course or evolution of strongyloidiasis; new strongyloidiasis is often paucisymptomatic or asymptomatic during COVID-19 infections	Small sample size with lack of generalizability; patients with a previous diagnosis of strongyloidiasis were excluded; cases with nonserological materials were excluded
Rodríguez-Guardado et al., 2022 (Spain)	Cross-sectional	To glean a better understanding of the diagnostic and therapeutic situation of strongyloidiasis in Spain and more specifically in patients coinfected with COVID-19	Investigational	121 responses from SEIMC members during February and March 2021	N/A	Most centers surveyed (84, 69.5%) had no specific strongyloidiasis screening protocol, and only 22 centers (18%) screened strongyloidiasis in patients with COVID-19	Survey-based design caused selection bias; the real prevalence was not estimated because participants were not asked about the number of cases screened; limited data on the characteristics of patients with hyperinfestation

COVID-19 = coronavirus disease 2019; SEIMC = Spanish Society of Infectious Diseases and Clinical Microbiology.