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Evernimicin-resistant 23S rDNA mutants and their evernimicin MICs
| Strain | 23S rDNA mutation | Evernimicin MIC (μg/ml) for:
|
|
|---|---|---|---|
| Spontaneous mutant | R6 transformant | ||
| ATCC 49619 | None | 0.047 | NA |
| ATCC 49619-1 | C2480T | 0.75 | 3.0 |
| ATCC 49619-2 | G2535A | 0.38 | 0.75 |
| SP#3 | None | 0.047 | NA |
| SP#3-1 | A2469C | 0.75 | 1.0 |
| SP#3-2 | G2536C | 0.38 | 0.75 |
