Table 1.

Adjusted hazard ratios (95% confidence intervals) for categorical psychosocial factors and risk of hard CVD incidence: The Multi-Ethnic Study of Atherosclerosis (2000–2012)

	Category 1	Category 2	Category 3	Category 4	Category5	P trend
Depressive symptoms range	0–2	3–5	6–10	11–15	≥ 16
Number of Event	97	76	96	43	55	-
Number of participants	1829	1549	1707	816	872	-
Model1†	1(reference)	0.90(0.66–1.22)	1.12(0.83–1.49)	1.01(0.69–1.47)	1.32(0.92–1.90)	0.09
Model2††	1(reference)	0.87(0.63–1.21)	1.18(0.86–1.59)	1.00(0.67–1.47)	1.30(0.89–1.90)	0.14
Chronic stress range	0	1	≥ 2
Number of Event	108	129	130	-	-	-
Number of participants	2308	2108	2332	-	-	-
Model1†	1(reference)	1.37(1.05–1.79)	1.51(1.16–1.96)	-	-	0.001
Model2††	1(reference)	1.35(1.02–1.79)	1.53(1.15–2.04)	-	-	0.003
Anxiety range	10–12	13–14	15–18	≥ 19
Number of Event	106	61	95	104	-	-
Number of participants	1766	1235	1957	1790	-	-
Model1†	1(reference)	0.94(0.68–1.31)	0.99(0.74–1.37)	1.25(0.93–1.67)	-	0.17
Model2††	1(reference)	0.66(0.29–1.49)	0.87(0.42–1.77)	1.51(0.80–2.86)	-	0.17
Emotional social support range	6–18	19–24	≥ 25
Number of Event	61	119	185	-	-	-
Number of participants	1022	2029	3712	-	-	-
Model1†	1(reference)	0.92(0.67–1.26)	0.70(0.52–0.95)	-	-	0.009
Model2††	1(reference)	0.89(0.64–1.24)	0.69(0.51–0.94)	-	-	0.009

†Model 1: adjusted for age, sex, race, education, and family history of heart attack

††Model 2: adjusted for model 1 plus smoking, alcohol status, diabetes status, current aspirin use, hypertension medication use, and total intentional exercise, LDL-C, HDL-C, systolic blood pressure, triglycerides, and BMI.

Higher scores on the psychosocial factors show more severe symptoms (Except emotional social support)