The parasite load of mice treated with the 80% methanolic crude fruit extract of Lagenaria siceraria following infection with P. berghei. Measured values are expressed as mean ± SEM (mice number in each group = 6). NC, negative control, 2% tween 80; ME, 80% methanol extract; CQ, positive control, chloroquine base; a, versus NC, 2% tween 80,10 ml/kg; e, versus 100 mg/kg; i, versus 200 mg/kg; o, versus 400 mg/kg; u, versus CQ10; πp<0.05. The numbers adjacent to the letters on the horizontal axis (10, 100, 200,400) denote the dose in mg/kg.