. 2023 Apr 14;9(4):e15453. doi: 10.1016/j.heliyon.2023.e15453

Table 1.

Rectal temperature and body weight changes of P. berghei infected mice, and treated with 80% methanolic crude fruit extract of Lagenaria siceraria.

Group	Body Weight (g)			Rectal Temperature (°C)
Group	D₀	D₄	Change (%)	D₀	D₄	Change (%)
NC	28.45 ± 0.81	24.342 ± 0.47	−14.26 ± 1.64	36.63 ± 0.24	34.28 ± 0.25	−6.44 ± 0.19
ME100	28.79 ± 0.61	26.06 ± 0.66	−9.49 ± 0.52a^πi^πo^πu^π	36.48 ± 0.31	35.09 ± 0.40	−3.82 ± 0.33a^πi^πo^πz^π
ME200	29.17 ± 0.68	27.73 ± 0.65	−1.02 ± 0.28a^πe^πo^πu^π	37.05 ± 0.33	36.12 ± 0.31	−2.51 ± 0.10a^πe^πo^πz^π
ME400	28.91 ± 0.62	28.62 ± 0.68	2.6644 ± 0.31a^πe^πi^πu^π	36.90 ± 0.62	36.50 ± 0.28	−1.08 ± 0.20a^πe^πi^πo^π
CQ10	28.80 ± 0.81	29.568 ± 0.83	0.30 ± 0.05a^π	36.98 ± 0.20	37.21 ± 0.18	0.67 ± 0.19a^π

Measured values are expressed as mean ± SEM (mice number in each group = 6). D₀ = pre-treatment value on day 0, D₄ = post-treatment value on day four, NC = negative control, ME = crude fruit extract of 80% methanol, CQ = chloroquine base. a, versus NC; e, versus 100 mg/kg; i, versus 200 mg/kg; o, versus 400 mg/kg; u, versus CQ10; ^πp<0.05. The numbers adjacent to the letters in the first column (10,100,200,400) denote the dose in mg/kg.