Table 1.
Clinical features of 34 patients enrolled in the study
| Characteristics | Number (%) |
|---|---|
| Age in years (Median - IQR) | 61 (54–71) |
| Sex | |
| Female | 20 (59) |
| Male | 14 (41) |
| Race | |
| White | 34 (100) |
| Body surface area, m2 (Median -IQR) | 1.9 (1.8–2.1) |
| Performance status | |
| 0 | 25 (74) |
| 1 | 9 (26) |
| 2 | 0 (0) |
| Primary tumor | |
| Right colon | 7 (21) |
| Left colon | 18 (53) |
| Rectum | 9 (26) |
| KRAS (N = 34), NRAS (N = 27) or BRAF (N = 31)a | |
| All wild-type | 8 (24) |
| Mutation | 26 (76) |
| Mismatch repair | |
| Proficient | 33 (97) |
| Deficient | 0 (0) |
| Unknown | 1 (3) |
| Primary tumor removed | |
| Yes | 25 (74) |
| No | 9 (26) |
| Number of previous regimens for metastatic disease, including rechallenge (Median - IQR) | 3 (2.25-3) |
| Current extent of disease, metastatic sitesb | |
| Liver | 32 (49) |
| Lung | 22 (65) |
| Lymph nodes | 8 (24) |
| Other | 13 (38) |
an indicates the number of patients who had the analysis performed. b Patients presented more than one metastatic site. IQR: interquartile range