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. Author manuscript; available in PMC: 2023 May 5.
Published in final edited form as: Kidney Int. 2022 Aug 31;102(6):1345–1358. doi: 10.1016/j.kint.2022.07.033

Figure 3. HF associated modules and their eigengenes’ association with duration of diabetic kidney disease.

Figure 3.

A. Cluster dendrogram of WGCNA based gene modules from glomerular transcription data from 29 participants. B. Three modules had ≥95% genes over-expressed in the HF group compared to pre-HF group. These modules were also significantly (*p<0.05, **p≤0.01) positively correlated with peak GFR at time of biopsy and negatively with mesangial cell volume (VVMC).

Abbreviations: ME- modules; PeakGFRatBx – Peak GFR at kidney biopsy/HF group; HbA1c- Hemoglobin A1c; mGFR-measured glomerular filtration rate; uACR- urine albumin-to-creatinine ratio; VVMC - mesangial fractional volume per glomerulus; FPW- foot process width