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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: J Biomed Mater Res A. 2023 Mar 2;111(7):910–920. doi: 10.1002/jbm.a.37521

Figure 1. Schematic of the foreign body response to an insulin infusion set.

Figure 1.

Protein aggregation and innate immune cell activation at the catheter tip of subcutaneously implanted pumps for continuous insulin infusion leads to a cascading foreign body responses that result in device failure, requiring changing of the insulin infusion set.