Date	Event	Description
18 February 2009	Amended	Converted to new review format. The Synopsis has been replaced by a new Plain Language Summary. Amendments in light of comments from the Group's Statistician have been made throughout the review.
18 February 2009	New search has been performed	Following on from as search of the Group's Cystic Fibrosis Trials Register four trials have been added to excluded studies (Chatham 2004; Grasso 2000; Stites 2006; Warwick 2004). An additional reference to an already excluded trial was also added (Braggion 1995).
15 November 2004	New citation required and conclusions have changed	Substantive amendment