Table 4.
Comparison between groups of pre- and post-operative NLR by various factors
| Factor | Group | Number | Pre-operative NLR | p- value | Post-operative NLR | p-value |
|---|---|---|---|---|---|---|
| Age, years | ≥65 | 22 | 1.7600 (1.37) | 0.251 | 4.3600 (7.00) | 0.647 |
| ＜65 | 86 | 1.6400 (1.25) | 4.1750 (3.32) | |||
| BMI, kg/m2 | ≥28 | 16 | 1.6350 (0.72) | 0.613 | 3.5200 (4.92) | 0.574 |
| ＜28 | 92 | 1.6500 (1.47) | 4.4150 (3.55) | |||
| Gender | Male | 79 | 1.6600 (1.47) | 0.462 | 4.4200 (3.96) | 0.577 |
| Female | 29 | 1.6200 (1.00) | 4.1400 (3.30) | |||
| Number of lesions | Multiple | 23 | 1.8000 (1.45) | 0.437 | 6.3100 (7.52) | 0.005 |
| Single | 85 | 1.6300 (1.36) | 3.9400 (2.71) | |||
| Maximum diameter of lesions, mm | ≥20 | 89 | 1.6200 (1.48) | 0.356 | 4.3100 (4.01) | 0.257 |
| ＜20 | 19 | 1.9200 (0.89) | 3.7500 (2.37) | |||
| Liver cirrhosis history | Yes | 96 | 1.6600 (1.39) | 0.622 | 4.3050 (3.62) | 0.996 |
| No | 12 | 1.3800 (1.73) | 3.8200 (6.04) | |||
| Drinking history | Yes | 21 | 1.7800 (2.03) | 0.364 | 4.9900 (8.45) | 0.060 |
| No | 87 | 1.6300 (1.28) | 4.1200 (3.20) | |||
| AFP, ng/ml | ≥400 | 17 | 1.9300 (1.69) | 0.604 | 4.9700 (6.56) | 0.610 |
| ＜400 | 91 | 1.6400 (1.44) | 4.2500 (3.32) | |||
| Child-pugh grades | A | 100 | 1.6650 (1.39) | 0.643 | 4.3050 (3.92) | 0.222 |
| B | 8 | 1.4850 (1.68) | 3.6450 (3.12) | |||
| ALT, U/L | ≥40 | 32 | 1.3300 (0.91) | 0.041 | 3.9450 (3.64) | 0.933 |
| ＜40 | 76 | 1.6750 (1.34) | 4.4250 (3.80) | |||
| AST, U/L | ≥40 | 27 | 1.3900 (1.07) | 0.253 | 3.5600 (4.63) | 0.305 |
| ＜40 | 81 | 1.6600 (1.48) | 4.4400 (3.35) | |||
| TBIL, μmol/L | ≥34 | 3 | 2.6300 (0.00) | 0.057 | 5.4700 (0.00) | 0.208 |
| ＜34 | 105 | 1.6400 (1.25) | 4.2100 (3.76) | |||
| ALB, G/L | ≥35 | 87 | 1.7500 (1.42) | 0.048 | 4.4400 (3.65) | 0.104 |
| ＜35 | 21 | 1.3700 (1.03) | 3.4200 (3.32) | |||
| Pre-operative leukocytes, x109/L | ≥5.575 | 36 | 1.8300 (1.26) | 0.097 | 4.7850 (6.87) | 0.093 |
| ＜5.575 | 72 | 1.5250 (1.03) | 3.9150 (3.13) | |||
| Post-operative leukocytes, x109/L | ≥6.61 | 56 | 1.7150 (1.37) | 0.259 | 4.5850 (4.96) | 0.035 |
| ＜6.61 | 52 | 1.5150 (1.21) | 3.7300 (2.51) | |||
| Pre-operative lymphocytes, x109/L | ≥1.455 | 63 | 1.4400 (1.12) | 0.018 | 3.7100 (4.28) | 0.313 |
| ＜1.455 | 45 | 1.8500 (1.44) | 4.7000 (2.76) | |||
| Post-operative lymphocytes, x109/L | ≥1.025 | 60 | 1.3400 (0.96) | 0.000 | 3.1050 (1.62) | 0.000 |
| ＜1.025 | 48 | 1.9800 (1.45) | 6.9550 (5.31) | |||
| Pre-operative neutrophils, x109/L | ≥3.431 | 33 | 2.6300 (1.63) | 0.000 | 5.5200 (7.12) | 0.005 |
| ＜3.431 | 75 | 1.3700 (0.79) | 3.8700 (2.50) | |||
| Post-operative neutrophils cells, x109/L | ≥4.975 | 47 | 1.8000 (1.25) | 0.029 | 6.3100 (6.00) | 0.000 |
| ＜4.975 | 61 | 1.4000 (1.14) | 3.4800 (2.41) |
AFP, alpha-fetoprotein; ALB, albumin; ALT, alanine transaminase; AST, aspartate transaminase; BMI, body mass index; NLR, neutrophil to lymphocyte ratio; TBIL, total bilirubin.
Notes：Pre- and post-operative NLR are expressed as median(Interquartile range). All other data are represented by n. Mann–Whitney U test was used to calculate p-value between two groups.