Table 6.

Haplotype association of IL1B htSNPs with lung cancer risk.

Haplotypea,b	Constructionc	Control frequency	Case frequency	OR (95% CI)	P value
1	GTC	0.3274	0.295	1.00	–
2	ACC	0.2323	0.2531	1.26 (1.00–1.59)	0.054
3	ATC	0.2328	0.24	1.17 (0.91–1.49)	0.22
4	ACA	0.0693	0.0947	1.55 (1.07–2.24)d	0.021d
5	GTA	0.0523	0.04	0.86 (0.51–1.46)	0.58
6	GCC	0.0432	0.0374	0.93 (0.55–1.59)	0.8
7	GCA	0.0353	0.0284	0.91 (0.49–1.69)	0.77
Rare	-	-	-	1.67 (0.49–5.71)	0.42

^aAdjusted for smoking duration, Global haplotype association P-value = 0.1

^bThree-locus order: rs1143633- rs3136558- rs1143630.

^cUnderlined indicates minor allele.

^dBoldface indicates statistical significance.