a, Predicted transcription binding sites for the DAR proximal to miR29B1 (chr7:130,878,800–130,879,437). Image from UCSC Genome Browser on Human (GRCh38/hg38). JASPAR CORE 2022, Minimum Score: 500. b, Quantification of Sytox-positive cells, CYTO-ID signal, STAT3 expression, and miR-29b-3p expression in fibroblasts from healthy control Young/Old, Pre-HD, and HD (n= 14 or 19 individual fibroblasts, statistical significance was determined by one-way ANOVA. ns, not significant; Mean±s.e.m.).