Table 1.
Characteristics of the Patients at Diagnosis
| Variable | HER2-Low (n = 561) | HER2-0 (n = 132) | Total | P value |
|---|---|---|---|---|
| Age | 48 (20–72) | 49 (26–70) | 48 (20–72) | 0.399 |
| Histologic type | 0.431 | |||
| Invasive ductal carcinoma | 543 (96.79%) | 126 (95.45%) | 669 | |
| Other | 18 (3.21%) | 6 (4.55%) | 24 | |
| T | 0.444 | |||
| T1 | 61 (10.87%) | 10 (7.58%) | 71 | |
| T2 | 385 (68.63%) | 97 (73.48%) | 482 | |
| T3 | 115 (20.50%) | 25 (18.94%) | 140 | |
| N | 0.008 | |||
| N0 | 205 (36.54%) | 58 (43.94%) | 263 | |
| N1 | 271 (48.31%) | 47 (35.61%) | 318 | |
| N2 | 74 (13.19%) | 19 (14.39%) | 93 | |
| N3 | 11 (1.96%) | 8 (6.06%) | 19 | |
| ER | 0.007 | |||
| ≤ 10 | 200 (45.65%) | 64 (48.48%) | 264 | |
| > 10 | 361 (64.35%) | 68 (51.52%) | 429 | |
| PR | 0.018 | |||
| ≤ 10 | 314 (55.97%) | 89 (67.42%) | 403 | |
| > 10 | 247 (44.03%) | 43 (32.58%) | 290 | |
| HR | 0.007 | |||
| HR+ | 397 (70.77%) | 77 (58.33) | 474 | |
| HR- | 164 (29.23%) | 55 (41.67%) | 219 | |
| Ki67 | 0.253 | |||
| ≤ 20 | 290 (51.69%) | 58 (43.94%) | 348 | |
| 21–30 | 128 (22.82%) | 33 (25.00%) | 161 | |
| > 30 | 143 (25.49%) | 41 (31.06%) | 184 | |
| p53 | 0.384 | |||
| ≤ 17.5 | 284 (50.62%) | 73 (55.30%) | 357 | |
| > 17.5 | 277 (49.38%) | 59 (44.70%) | 336 | |
| pCR | 0.468 | |||
| pCR | 68 (12.12%) | 19 (14.39%) | 87 | |
| Non-pCR | 493 (87.88) | 113 (85.61%) | 606 |