Table 3.

Survival Analysis

Cortical structure	Test 1, Multivariate Cox		Test 2, Wilcoxon Rank-Sum Test			Test 3, KM
	HR (CI: L, U)	p	Median OS (Low, High CT) days	W	p	Chi2	p
Hemispheric CT	0.09(0.02, 0.44)	.003*	311,525	2120	.0001*	13.42	.0003*
Lobar CT
Frontal	0.20(0.05 0.71)	.013	314,525	2221	.0004*	10.7	.001*
Parietal	0.11(0.03, 0.46)	.003*	289,527	1879	2.7E−5*	21.3	3.9E−6*
Temporal	0.14(0.04, 0.50)	.003*	311,527	2078	5.6E−5*	10.1	.002*
Parcel CT
Fusiform	0.15(0.05, 0.48)	.0007*	334,525	2163	.0002*	12.23	.0005*
Inferior parietal	0.17(0.05, 0.56)	.004	321,508	2284	.0008*	10.50	.0012*
Lateral orbitofrontal	0.24(0.08, 0.75)	.014	324,530	2221	.0004*	9.43	.0021
Paracentral	0.32(0.14, 0.75)	.008	324,480	2171	.0002*	13.57	.0002*
Parsopercularis	0.23(0.08, 0.63)	.005	312,522	2259	.0006*	9.21	.0024
Precuneus	0.26(0.09, 0.73)	.010	314,530	1970	1.1E−5*	18.81	1.4E−5*
Rostral middlefrontal	0.27(0.10, 0.73)	.010	312,525	2148	.0002*	16.5	4.8E−5*
Superior frontal	0.28 (0.09, 0.82)	.020	334,491	2367	.0002*	9.16	.002
Superior-parietal	0.34 (0.13, 0.88)	.011	334,472	2344	.0018	10.83	.0009*
Superior temporal	0.34 (0.13, 0.88)	.026	314,525	2188	.0002*	14.38	.0001*
Supramarginal	0.26 (0.08, 0.83)	.022	314,472	2250	.00057*	10.39	.0013*

Abbreviations: CT, cortical thickness; HR, hazard ratio; OS, overall survival.

Test 1: Multivariate Cox proportional hazards model was performed (with age, sex and hemisphere). Test 2: Wilcoxon rank-sum test of median overall survival of low versus high cortical thickness patients (WRS). Test 3: Kaplan–Meier test of survival difference (KM; *p < .05, Bonferroni correction).