FIG. 1.

Survival in SW mice treated orally with 100 mg of trovafloxacin per kg and injected i.v. with 1,000 μg of LPS 1 h later (A) or treated orally with 250 mg of ciprofloxacin per kg and injected with LPS 1 h later (B). The P values, as determined by Kaplan-Meier product limited-survival analysis, were 0.001 for trovafloxacin and 0.008 for ciprofloxacin.