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Representative 20 μm full cerebellar sagittal slices stained with Anti-Calb1 (yellow), counterstained with DAPI (blue). The L7-Slc9a6-GFP AAV prevented PC loss in shaker rats compared with those administered the L7-GFP control AAV. Shown are representative sagittal slices across groups. Notably, PCs tend to be preserved in the flocculonodular lobule 10. Even a relatively small degree of PC rescue led to substantial motor recovery (Fig. 2).
