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. 2023 May 5;18(5):e0285360. doi: 10.1371/journal.pone.0285360

Table 2. Comparison of OCTA parameters between Black and White subjects.

Macular Capillary Parameter All White Subjects All Black Subjects P-valuea Non-HTN White Subjects Non-HTN Black Subjects P-valueb
SCP VD (%)
3x3 mm macular area 45.74 ± 4.22 46.03 ± 4.41 0.28 46.02 ± 3.87 47.92 ± 3.40 0.33
Fovea 21.07 ± 8.07 15.03 ± 7.54 0.02* 20.93 ± 7.79 17.37 ± 8.01 0.13
Parafovea 48.49 ± 3.99 49.33 ± 4.41 0.09 48.79 ± 3.69 51.15 ± 3.44 0.15
ICP VD (%)
3x3 mm macular area 43.74 ± 4.10 43.88 ± 4.30 0.42 44.17 ± 3.60 43.29 ± 3.50 0.053
Fovea 35.44 ± 6.51 28.03 ± 8.19 < 0.001* 35.52 ± 6.84 30.95 ± 8.14 0.008*
Parafovea 44.98 ± 4.66 45.77 ± 4.66 0.98 45.38 ± 4.13 44.93 ± 3.41 0.28
DCP VD (%)
3x3 mm macular area 40.91 ± 10.75 42.60 ± 8.47 0.73 39.10 ± 10.19 43.03 ± 7.69 0.74
Fovea 25.32 ± 10.36 23.58 ± 8.96 0.33 23.21 ± 8.67 25.77 ± 9.8 0.76
Parafovea 43.11 ± 11.23 45.20 ± 8.77 0.59 41.33 ± 10.91 45.34 ± 8.01 0.70
FAZ
Area (mm^2) .23 ± .10 .35 ± .12 <0.001* 0.24 ± .11 0.34 ± .13 0.003*
Perimeter (mm) 1.88 ± .44 2.38 ± .39 <0.001* 1.92 ± .45 2.31 ± .47 0.003*
Acircularity Index (AI) 1.14 ± .048 1.14 ± .055 0.16 1.15 ± .05 1.14 ± .05 0.21
FD-300 area density (%) 49.20 ± 3.53 51.21 ± 3.76 0.001* 49.92 ± 3.30 51.95 ± 3.54 0.02*
Choriocapillaris BFA (%)
3x3 mm macular area 69.77 ± 3.07 66.10 ± 4.71 0.006* 69.83 ± 2.86 67.29 ± 3.31 0.01*
Fovea 69.95 ± 4.40 66.86 ± 3.77 0.03* 69.72 ± 3.64 67.83 ± 4.35 0.26
Parafovea 69.71 ± 3.94 65.81 ± 3.94 0.008* 69.85 ± 2.87 67.22 ± 3.40 0.01*

aP-values were calculated using a mixed-effects linear regression model that adjusted for two eyes of the same patient and hypertension.

bP-values were calculated using a mixed-effects linear regression model that adjusted for two eyes of the same patient in a cohort without hypertension.

*Significant at P < 0.05.

HTN: Hypertension; VD: Vessel density, FAZ: Foveal avascular zone, BFA: Blood blow area, SCP: Superficial capillary plexus, ICP: Intermediate capillary plexus, DCP: Deep capillary plexus.