Table 1.
Demographic and Clinical Data of the Studied Groups
| Control N=20 | Cirrhosis N=50 | HCC N=50 | P. value | ||||
|---|---|---|---|---|---|---|---|
| Cirrhosis Vs Control |
HCC Vs Control |
HCC Vs Cirrhosis |
|||||
| Age | 40.3±3.6 | 40.3±8.7 | 58.4±8.1 | 0.9 | 0.001** | 0.001** | |
| Sex | Female | 8 (40.0%) | 9 (18.0%) | 8 (16.0%) | 0.01* | 0.01* | 0.6 |
| Male | 12 (60.0%) | 41 (82.0%) | 42 (84.0%) | ||||
| HBV | Normal | 20 (100.0%) | 0 (0.0%) | 0 (0.0%) | 0.001** | 0.001** | N.A |
| HBV | 0 (0.0%) | 0 (0.0%) | 1 (2.0%) | N.A | 0.15 | 0.15 | |
| HCV | 0 (0.0%) | 50 (100.0%) | 26 (52.0%) | 0.001** | 0.001** | 0.01* | |
| Non B Non C | 0 (0.0%) | 0 (0.0%) | 23 (46.0%) | N.A | 0.01* | 0.01* | |
| Tumor grade | Normal | 20 (100.0%) | 50 (100.0%) | 0 (0.0%) | N.A | 0.001** | 0.001** |
| I | 0 (0.0%) | 0 (0.0%) | 31 (62.0%) | N.A | 0.01* | 0.01* | |
| II | 0 (0.0%) | 0 (0.0%) | 19 (38.0%) | N.A | 0.01* | 0.01* | |
| Number of Masses | Normal | 20 (100.0%) | 50 (100.0%) | 0 (0.0%) | N.A | 0.001** | 0.001** |
| 1 | 0 (0.0%) | 0 (0.0%) | 34 (68.0%) | N.A | 0.001** | 0.001** | |
| 2 | 0 (0.0%) | 0 (0.0%) | 9 (18.0%) | N.A | 0.02* | 0.02* | |
| 3 | 0 (0.0%) | 0 (0.0%) | 7 (14.0%) | N.A | 0.03* | 0.03* | |
| Size of the Mass | Normal | 20 (100.0%) | 50 (100.0%) | 0 (0.0%) | N.A | 0.001** | 0.001** |
| 1-3 cm | 0 (0.0%) | 0 (0.0%) | 17 (34.0%) | N.A | 0.01* | 0.01* | |
| >3cm | 0 (0.0%) | 0 (0.0%) | 33 (66.0%) | N.A | 0.001** | 0.001** | |
| AFP level | <400 | 20 (100.0%) | 50 (100.0%) | 37 (74.0%) | N.A | 0.01* | 0.01* |
| >400 ng/ml | 0 (0.0%) | 0 (0.0%) | 13 (26.0%) | ||||
| Hepatomegaly | Absent | 20 (100.0%) | 18 (36.0%) | 10 (20.0%) | 0.01* | 0.01* | 0.01* |
| Present | 0 (0.0%) | 32 (64.0%) | 40 (80.0%) | ||||
| Splenomegaly | Absent | 20 (100.0%) | 22 (44.0%) | 15 (30.0%) | 0.01* | 0.01* | 0.01* |
| Present | 0 (0.0%) | 28 (56.0%) | 35 (70.0%) | ||||
| Ascites | Absent | 20 (100.0%) | 23 (46.0%) | 11 (22.0%) | N.A | 0.04* | 0.01* |
| Present | 0 (0.0%) | 27 (54.0%) | 39 (78.0%) | ||||
| Oedema Lower Limbs | Absent | 20 (100.0%) | 50 (100.0%) | 32 (64.0%) | N.A | 0.01* | 0.01* |
| Present | 0 (0.0%) | 0 (0.0%) | 18 (36.0%) | ||||
| Portal Vein Thrombosis | Absent | 20 (100.0%) | 28 (56.0%) | 32 (64.0%) | N.A | 0.05* | 0.01* |
| Present | 0 (0.0%) | 22 (44.0%) | 18 (36.0%) | ||||
Age was represented as Mean± SD, the data were analyzed by t test. While HBV, CHILD grade, Number of masses, Size of the mass, AFP level, Hepatomegaly, Splenomegaly, Ascites, Oedema Lower Limbs, and Portal Vein Thrombosis were represented as frequency and percent, the data were analyzed by X2 test; * P value <0.05 is significant, ** P value <0.01 is highly significant, N.A, Not Applicable.