Table 3.
Protein Levels of GPC3, VEGF and GP73 in the Studied Groups
| Control N=20 | Cirrhosis N=50 | HCC N=50 | P. value | |||
|---|---|---|---|---|---|---|
| Cirrhosis Vs Control |
HCC Vs Control |
HCC Vs Cirrhosis |
||||
| GPC3 pg/ml x103 | 55.8 (53.8- 78.1) | 102.5 (48.7- 187.9) | 118.8 (20.2- 207.2) | 0.05* | 0.03* | 0.9 |
| VEGF pg/ml | 14.6 (10.4- 31.9) | 151.1 (65.6- 257.2) | 171.7 (83.7- 312.7) | 0.001** | 0.001** | 0.5 |
| GP73 pg/ml x103 | 12.2 (11.2- 12.6) | 23.1 (16.0- 28.4) | 33.3 (22.5- 57.5) | 0.001** | 0.001** | 0.001** |
The studied biomarkers were represented as Median with Interquartile range (25% -75%), the data were analyzed by Mann-Whitney U test; * P value <0.05 is significant, ** P value <0.01 is highly significant.