Summary of findings 3. Weekly educational texts messages versus once every other week educational text messages for the management of inflammatory bowel disease.

Weekly educational texts messages versus once every other week educational text messages for the management of inflammatory bowel disease
Patient or population: people with inflammatory bowel disease Setting: hospital in USA Intervention: every other week educational text messages Comparison: weekly educational text messages
Outcomes	Impact	№ of participants (studies)	Certainty of the evidence (GRADE)	Comments
Disease activity (12 months)	UC participants (SCCAI score, minimum 0, maximum 19; low score = better result): Mean (SD) disease activity for the every other week UC participants was 1.7 (1.9) Mean (SD) disease activity for the weekly UC participants was 2.0 (1.8).   CD participants (HBI score, minimum 0, maximum 18; low score = better result): Mean (SD) disease activity for the every other week CD participants was 4.2 (3.9) Mean (SD) disease activity for the weekly CD participants 3.2 (3.4).	1 study (131 CD and 62 UC participants)	⊕⊝⊝⊝ Very lowa	‐
Flare‐ups or relapse (continuous)	‐	‐	‐	‐
Flare‐ups or relapse (dichotomous)	‐	‐	‐	‐
Quality of life, IBDQ (32 minimum score ‐ 224 maximum score; high score = better quality of life) (12 months)	Mean (SD) quality of life scores for the every other week participants was 181.5 (28.2) and for the weekly participants was 179.2 (32.8)	1 study (193 participants)	⊕⊝⊝⊝ Very lowa	‐
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CD: Crohn's disease; HBI: Harvey‐Bradshaw Index for Crohn's Disease; IBDQ: Inflammatory Bowel Disease Questionnaire; SCCAI: Simple Clinical Colitis Activity Index; SD: standard deviation; UC: ulcerative colitis
GRADE Working Group grades of evidence High certainty: we are very confident that the true effect lies close to that of the estimate of the effect. Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect. Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.

^aDowngraded three levels: one level due to concerns with risk of bias due to blinding, and two levels due to serious concerns with imprecision due to very low participant numbers